Publications (including Japanese publications)

ORCID iD iconorcid.org/0000-0002-8070-8708

2025

  1. Taisei Kanamori, Shogo Yasuda, Runjing Duan, Mei Ohashi, Mai Amou, Kanato Hori, Ryota Tsuda, Taiki Fujimoto, Kenjirou Higashi, Wei Xu, Takuro Niidome, Hiroto Hatakeyama, Cholesterol depletion suppresses thermal necrosis resistance by alleviating an increase in membrane fluidity, Sci. Rep., in press
  2. Masaya Harada, Wei Xu, Yusuke Kambe, Tsunenori Kameda, Shoji Nagaoka, Makoto Sasaki, Takuro Niidome, The effect of degumming conditions on the functionality of silk fibroin films, Polym. J., in press

2024

  1. Junya Michibata, Yoshimasa Kawaguchi, Hisaaki Hirose, Akiko Eguchi, Sayaka Deguchi, Kazuo Takayama, Wei Xu; Takuro Niidome, Yoshihiro Sasaki, Kazunari Akiyoshi, Shiroh Futaki, Polysaccharide-based coacervate microgel bearing cationic peptides that achieve dynamic cell-membrane structure alteration and facile cytosolic infusion of IgGs, Bioconjugate Chem., 35, 1888–1899
  2. Wei Xu, Sayo Maruyama, Akito Sato, Takuro Niidome, Bacterial membrane vesicles combined with nanoparticles for bacterial vaccines and cancer immunotherapy, Colloids Surf. B, 243 114125-114125 (2024)
  3. Ryoko Nawata, Sayo Maruyama, Wei Xu, Takuro Niidome, Encapsulation of silver nanoplates into PLGA nanoparticles and the antibacterial activity against intracellular bacteria, Chem. Lett., 53, upae084 (2024)
  4. Shunsuke Yoshie, Masashi Kuriyama, Masashi Maekawa, Wei Xu, Takuro Niidome, Shiroh Futaki, Hisaaki Hirose, ATP2B4 is an essential gene for epidermal growth factor-induced macropinocytosis in A431 cells, Genes to Cells, 29, 512–520 (2024)
  5. Hirotaka Watanabe, Wei Xu, Haruka Uno, Yuki Uraya, Masanori Kugita, Yoshihiro Komohara, Takuro Niidome, Makoto Sasaki, Ichiro Shimizu, Nobuyuki Fujita, Yusuke Kawano Fluoride-treated rare earth-free magnesium alloy ZK30: An inert and bioresorbable material for bone fracture treatment devices, J. Biomed. Mater. Res. A, 112, 963-972 (2024)

2023

  1. Waliul Islam, Hiroyasu Tsutsuki, Azizur Rahman, Ayaka Harada, Tianli Zhang, Katsuhiko Ono, Rayhanul Islam, Foysal Hossen, Takuro Niidome, Tomohiro Sawa, Jun Fang, Styrene maleic acid polymer-encapsulated chlorophyll as a stable micellar nanoprobe for advanced anticancer photodynamic therapy, ACS Appl. Polym. Mater., 5, 10289–10302 (2023)
  2. Tomohiro Sawa, Touya Toyomoto, Katsuhiko Ono, Tomoo Shiba, Kenta Momitani, Tianli Zhang, Hiroyasu Tsutsuki, Takeshi Ishikawa, Kanae Hoso, Koma Hamada, Azizur Rahman, Liping Wen, Keiichi Yamamoto, Masao Matsuoka, Kenjiro Hanaoka, Takuro Niidome, Takaaki Akaike, Alkyl gallates inhibit serine O-acetyltransferase in bacteria and enhance susceptibility of drug-resistant gram-negative bacteria to antibiotics, Front. Microbiol., DOI 10.3389/fmicb.2023.1276447 
  3. Wei Xu, Yuta Kadoya, Kaito Sennari, Waliul Islam, Tianli Zhang, Tomohiro Sawa, Fumika Akizuki, Hisaaki Hirose, Shiroh Futaki, Yukio Fujiwara, Yoshihiro Komohara, Takuro Niidome, Disulfiram encapsulated in polymer nanoparticles ameliorates thioacetamide-induced liver injury, J. Drug Deliv. Sci. Technol., 88, 104981 (2023) 
  4. Yusuke Nakayama, Yutaro Ito, Tsuyoshi Fukaminato, Wei Xu, Takuro Niidome, Seiji Kurihara, Sunnam Kim, Water-Soluble Hyperbranched Polymer with High Curcumin Content, J. Appl. Polym. Sci., 140, e54673 (2023) 
  5. Ayaka Harada, Wei Xu, Katsuhiko Ono, Hiroyasu Tsutsuki, Kinnosuke Yahiro, Tomohiro Sawa, Takuro Niidome, Modification of silver nanoplates with cell-binding subunit of bacterial toxin and their antimicrobial activity against intracellular bacteria, ACS Appl. Bio Mater, 6, 3387–3394 (2023)
  6. Keiki Muranaka, Takuro Niidome, Maria Leilani Torres, Alexander Heisterkamp, Mitsuhiro Terakawa, Formation of gold nanoparticles inside a hydrogel by multiphoton photoreduction for plasmonic sensing, Plasmonics, 18, 751–760 (2023)

2022

  1. Waliul Islam, Hiroyasu Tsutsuki, Katsuhiko Ono, Ayaka Harada, Kozo Shinozaki, Takuro Niidome, Jun Fang, Tomohiro Sawa, Structural determination of the nanocomplex of borate with styrene-maleic acid copolymer-conjugated glucosamine used as a multifunctional anticancer drug, ACS Appl. Bio Mater, 12, 5953–5964 (2022)
  2. Waliul Islam, Takuro Niidome, Tomohiro Sawa, The enhanced permeability and retention effect as a ubiquitous and epoch-Making phenomenon in the selective targeting of drugs to solid tumors, J. Pers. Med., 12, 1964 (2022)
  3. Yuko T Sato, Daisuke Asai, Keiko Terada, Jeong-Hun Kang, Takeshi Mori, Takuro Niidome, Hideki Nakashima, Yoshiki Katayama, A model of transcriptional activation of DNA by loosening of chromatin structure, Chem. Lett., 51, 1109–1112 (2022) 
  4. Ayaka Harada, Hiroyasu Tsutsuki, Tianli Zhang, Kinnosuke Yahiro, Tomohiro Sawa, Takuro Niidome, Controlled delivery of an anti-inflammatory toxin to macro-phages by mutagenesis and nanoparticle modification, Nanomaterials, 12, 2161 (2022)
  5. Makoto Sasaki, Wei Xu, Yuki Koga, Yuki Okazawa, Akira Wada, Ichiro Shimizu,Takuro Niidome, Effect of parylene C on the corrosion resistance of bioresorbable cardiovascular stents made of magnesium alloy 'Original ZM10', Materials, 15, 3132 (2022)
  6. Mai Shinohara, Wei Xu, Sun-nam Kim, Tuyoshi Fukaminato, Takuro Niidome, Seiji Kurihara, Photo-control of cellular uptake by the selective adsorption of spiropyran derivatives on albumin, Chem. Lett., 51, 594–597 (2022) 
  7. Wei Xu, Makoto Sasaki, Takuro Niidome, Sirolimus release from biodegradable polymers for coronary stent, Pharmaceutics, 14, 492 (2022)
  8. Emi Takeda, Wei Xu, Mitsuhiro Terakawa, Takuro Niidome, Tailored structure and antibacterial properties of silica-coated silver nanoplates by pulsed laser irradiation, ACS Omega, 7, 7251–7256 (2022)
  9. Mai Shinohara, Yuya Ashikaga, Wei Xu, Sunnam Kim, Tuyoshi Fukaminato, Takuro Niidome, Seiji Kurihara, Photochemical OFF/ON cytotoxicity switching by using a photochromic surfactant with visible light irradiation, ACS Omega, 7, 6093–6098 (2022)

2021

  1. Waliul Islam, Shintaro Kimura, Rayhanul Islam, Ayaka Harada, Katsuhiko Ono, Jun Fang, Takuro Niidome, Tomohiro Sawa, Hiroshi Maeda, EPR effect enhancers strongly potentiate tumor-targeted delivery of nanomedicines to advanced cancers: Further extension to enhancement of the therapeutic effect, J. Pers. Med., 11, 487 (2021)
  2. Mio Tameike, Takuro Niidome, Yasuro Niidome, Junichi Kurawaki, Novel photoluminescent gold complexes prepared at octanethiol–water interfaces: Control of optical properties by addition of silver ions, Bull. Chem. Soc. Jpn., 94, 1875-1881 (2021)
  3. Waliul Islam, Yoshitaka Matsumoto, Jun Fang, Ayaka Harada, Takuro Niidome, Katsuhiko Ono, Hiroyasu Tsutsuki, Tomohiro Sawa, Takahisa Imamura, Kazuo Sakurai, Nobuyoshi Fukumitsu, Hirofumi Yamamoto, Hiroshi Maeda, Polymer-conjugated glucosamine complexed with boric acid shows tumor-selective accumulation and simultaneous inhibition of glycolysis, Biomaterials, 269, 120631 (2021)
  4. Yong Il Park, Seung-Hae Kwon, Gibok Lee, Keiichi Motoyama, Min Woo Kim, Min Lin, Takuro Niidome, Jung Hoon Choi, Ruda Lee, pH-sensitive multi-drug liposomes targeting folate receptor β for efficient treatment of non-small cell lung cancer, J. Controlled Release, 330, 1-14 (2021)

2020

  1. Yuxiang Xiao, Wei Xu, Yoshihiro Komohara, Yukio Fujiwara, Hisaaki Hirose, Shiroh Futaki, Takuro Niidome, Effect of surface modifications on cellular uptake of gold nanorods in human primary cells and established cell lines, ACS Omega, 5, 32744-32752 (2020)
  2. Sho Ueno, Min Woo Kim, Gibok Lee, Yong Il Park, Takuro Niidome, Ruda Lee, Development of ErbB2-targeting liposomes for enhancing drug delivery to ErbB2-positive breast cancer, Pharmaceutics, 12, 585 (2020)
  3. Toru Taharabaru, Ryoma Yokoyama, Taishi Higashi, Ahmed Fouad Abdelwahab Mohammed, Masamichi Inoue, Yuki Maeda, Takuro Niidome, Risako Onodera, Keiichi Motoyama, Genome editing in a wide area of brain using dendrimer-based ternary polyplex of Cas9 ribonucleoprotein, ACS Appl. Mater. Interfaces, 12, 21386–21397 (2020)
  4. Hiroyasu Tsutsuki, Tianli Zhang, Ayaka Harada, Azizur Rahman, Katsuhiko Ono, Kinnosuke Yahiro, Takuro Niidome, Tomohiro Sawa, Involvement of protein disulfide isomerase in Subtilase cytotoxin-induced cell death in HeLa cells, Biochem. Biophys. Res. Co., 525, 1068-1073 (2020)
  5. Min Woo Kim, Gibok Lee, Takuro Niidome, Ruda Lee, Yong Il Park, Platelet-like gold nanostars for cancer therapy: the ability to treat cancer and evade immune reactions, Front. Bioeng. Biotechnol., 8, 133 (2020)
  6. Ayaka Harada, Hiroyasu Tsutsuki, Tianli Zhang, Ruda Lee, Kinnosuke Yahiro, Tomohiro Sawa, Takuro Niidome, Preparation of biodegradable PLGA-nanoparticles used for pH-sensitive intracellular delivery of an anti-inflammatory bacterial toxin to macrophages, Chem. Pharm. Bull., 68, 363–368 (2020)
  7. Wei Xu, Kai Yagoshi, Tetsuo Asakura, Makoto Sasaki, Takuro Niidome, Silk fibroin as a coating polymer for sirolimus-eluting magnesium alloy stents, ACS Appl. Bio Mater, 3, 531-538 (2020)
  8. Wei. Xu, Kensuke Sato, Yuki Koga, Makoto Sasaki, Takuto Niidome, Corrosion resistance of HF-treated Mg alloy stent following balloon expansion and its improvement through biodegradable polymer coating, J. Coat. Technol. Res. 17, 1023-1032 (2020)

2019

  1. Min Woo Kim, Takuro Niidome, Ruda Lee, Glycol chitosan-docosahexaenoic acid liposomes for drug delivery: synergistic effect of doxorubicin-rapamycin in drug-resistant breast cancer, Mar. Drugs, 17, 581 (2019)
  2. Manan Machida, Takuro Niidome, Hiroaki Onoe, Alexander Heisterkamp, Mitsuhiro Terakawa, Spatially-targeted laser fabrication of multi-metal microstructures inside a hydrogel, Optics Express, 27, 14657-14666 (2019)
  3. Ayaka Harada, Hiroaki Ichimaru, Takayuki Kawagoe, Masayuki Tsushida, Yasuro Niidome, Hiroyasu Tsutsuki, Tomohiro Sawa, Takuro Niidome, Gold-treated silver nanoparticles have enhanced antimicrobial activity, Bull. Chem. Soc. Jpn., 92, 297-301 (2019)
  4. Yoshihiro Higuchi, Takuro Niidome, Yuji Miyamoto, Yoshihiro Komohara, Tomotake Tokunou, Toru Kubota, Takahiko Horiuchi, Accumulation of gold nano-rods in the failing heart of transgenic mice with the cardiac-specific expression of TNF-α, Heart and Vessels, 34, 538-544 (2019)

2018

  1. Hiroaki Ichimaru, Ayaka Harada, Soichiro Yoshimoto, Yuta Miyazawa, Daigou Mizoguchi, Kaung Kyaw, Katsuhiko Ono, Hiroyasu Tsutsuki, Tomohiro Sawa, Takuro Niidome, Gold coating of silver nanoplates for enhanced dispersion stability and efficient antimicrobial activity against intracellular bacteria, Langmuir, 34, 10413-10418 (2018)
  2. Wei Xu, Kai Yagoshi, Yuki Koga, Makoto Sasaki, Takuro Niidome, Optimized polymer coating for magnesium alloy-based bioresorbable scaffolds for long-lasting drug release and corrosion resistance, Colloids. Surf. B: Biointerfaces, 163, 100-106 (2018)
  3. Kaung Kyaw, Nana Motoyama, Hiroaki Ichimaru, Ayaka Harada, Shigeru Morimura, Katsuhiko Ono, Hiroyasu Tsutsuki, Tomohiro Sawa, Yuta Miyazawa, Daigou Mizoguchi, Takuro Niidome, A simple PLGA-AgNPL film for antibiofilm formation by contact bactericidal activity, Chem. Lett., 47, 308-310 (2018)

2017

  1. Kaung Kyaw, Hiroaki Ichimaru, Takayuki Kawagoe, Mitsuhiro Terakawa, Yuta Miyazawa, Daigou Mizoguchi, Masayuki Tsushida, Takuro Niidome, Effects of pulsed laser irradiation on gold-coated silver nanoplates and their antibacterial activity, Nanoscale, 9, 16101-16105 (2017)
  2. AkiraTsuchiya, Jeong-Hun Kang, Takeshi Mori, Yuki Naritomi, Satoshi Kushio, Takuro Niidome, Katsuro Tachibana, Yoko Takahashi, Yoichi Negishi, Yusuke Oda, Ryo Suzuki, Kazuo Maruyama, Yoshiki Katayama, Efficient delivery of signal-responsive gene carriers for disease-specific gene expression via bubble liposomes and sonoporation, Colloids Surf. B, 160, 60-64 (2017)
  3. Aung Thu Haine, Yuji Miyamoto, Taishi Higashi, Keiichi Motoyama, Hidetoshi Arima, Takuro Niidome, Comparison of ovalbumin and ovalbumin epitope peptide for transdermal delivery and vaccination mediated by the photothermal effect of gold nanorods, J. Biomater. Sci. Polym. Ed., 28, 1888-1898 (2017)
  4. Aung Thu Haine, Yuki Koga, Yuta Hashimoto, Taishi Higashi, Keiichi Motoyama, Hidetoshi Arima, Takuro Niidome, Enhancement of transdermal protein delivery by photothermal effect of gold nanorods coated on polysaccharide-based hydrogel, Eur. J. Pharm. Biopharm., 119, 91-95 (2017)
  5. Misato Takizaki, Shun-ichiro Muranaka, Aung Thu Haine, Shigenori Tokunaga, Shigeru Morimura, Takuro Niidome, Enhancing mechanism of gene transfection by heat shock, Chem. Lett., 46, 1158-1160 (2017)
  6. Chaoya Ma, Hasita Horlad, Cheng Pan, Hiromu Yano, Koji Ohnishi, Yukio Fujiwara, Masao Matsuoka, Aeju Lee, Takuro Niidome, Ryuya Yamanaka, Motohiro Takeya, Yoshihiro Komohara, Stat3 inhibitor abrogates the expression of PD-1 ligands on lymphoma cell lines, J. Clin. Exp. Hematop., 57, 21-25 (2017)
  7. Aung Thu Haine, Takuro Niidome, Gold nanorods as nanodevices for bioimaging, photothermal therapeutics and drug delivery, Chem. Pharm. Bull., 65, 625-628 (2017)
  8. Kaung Kyaw, Ayaka Harada, Hiroaki Ichimaru, Takayuki Kawagoe, Kinnosuke Yahiro, Shigeru Morimura, Katsuhiko Ono, Hiroyasu Tsutsuki, Tomohiro Sawa, Takuro Niidome, Silver nanoparticles as potential antibiofilm agents against human pathogenic bacteria, Chem. Lett., 46, 594-596 (2017)
  9. Yoshihiro Komohara, Ryuta Kawauchi, Erika Makiyama, Kazuki Mikami, Hasita Horlad, Yukio Fujiwara, Tetsuya Kida, Motohiro Takeya, Takuro Niidome, Selected depletion of cultured macrophages by magnetite nanoparticles modified with gelatin, Exp. Ther. Med., 14, 1640-1646 (2017)

2016

  1. Masayuki Nakano, Kinnosuke Yahiro, Eiki Yamasaki, Hisao Kurazono, Junko Akada, Yoshio Yamaoka, Takuro Niidome, Masanori Hatakeyama, Hidekazu Suzuki, Taro Yamamoto, Joel Moss, Hajime Isomoto, Toshiya Hirayama, Helicobacter pylori VacA acting through receptor protein tyrosine phosphatase α; is critical for CagA phosphorylation in AZ-521 cells, Dis. Model. Mech., 9, 1473-1481 (2016)
  2. Yasuro Niidome, Aung Thu Haine, Takuro Niidome, Anisotropic Gold-based Nanoparticles: Preparation, Properties, and Applications, Chem. Lett., 45, 488-498 (2016)

2015

  1. Chie Kojima, Ugir Hossain Sk, Daichi Fukushima, Kotaro Irie, Naotoshi Akazawa, Masafumi Umeda, Takuro Niidome, Effect of main chain conformation to thermosensitivity in elastin-like peptide-grafted polylysine, RSC Adv., 5. 104900–104906 (2015)
  2. Eun Kyung Lee, Chan Woo Kim, Hiroyuki Kawanami, Akihiro Kishimura, Takuro Niidome, Takeshi Mori, Yoshiki Katayama, Utilization of a PNA-peptide conjugate to induce a cancer protease-responsive RNAi effect, RSC Adv., 5, 85816-85821 (2015)
  3. Aung Thu Haine, Takuro Niidome, Drug delivery systems controlled by irradiation of near infrared light, J. Photopolym. Sci. Technol., 78, 705-710 (2015)
  4. Takuro Niidome, Masanori Fujii, Naotoshi Nakashima, Yoshiki Katayama, Yasuro Niidome, Imaging mass spectrometry of gold nanorods distributed in tumor tissues, Chem. Lett., 44, 931-933 (2015)
  5. Daiki Funamoto, Daisuke Asai, Chan Woo Kim, Yuta Nakamura, Eun Kyung Lee, Takanobu Nobori, Takuro Niidome, Takeshi Mori, Yoshiki Katayama, Tandemly repeated peptide for cancer-specific gene carrier prepared by native chemical ligation, Chem. Lett. 44, 474–476 (2015)
  6. Dakrong Pissuwan, Takuro Niidome, Polyelectrolyte-coated gold nanorods and their biomedical applications, Nanoscale, 7, 59-65 (2015)

2014

  1. Masayoshi Matsuda, Wataru Hatanaka, Masafumi Takeo, Chan Woo Kim, Takuro Niidome, Tatsuhiro Yamamoto, Akihiro Kishimura, Takeshi Mori, Yoshiki Katayama, Short peptide motifs for long-lasting anchoring to the cell surface, Bioconjugate Chem., 25, 2134-2143 (2014)
  2. Riki Toita, Chan Woo Kim, Jeong-Hun Kang, Takuro Niidome, Takeshi Mori, Yoshiki Katayama, Effect of peptide content on the regulation of transgene expression by protein kinase C<alpha>-responsive linear polyethylenimine-peptide conjugates, Colloids Surf. B: Biointerfaces, 123, 123-129 (2014)
  3. Takuro Niidome, Risa Gokuden, Kazuto Watanabe, Takeshi Mori, Tatsuya Naganuma, Hideo Utsumi, Kazuhiro Ichikawa, Yoshiki Katayama, Nitroxyl radicals-modified dendritic poly(L-lysine) as a contrast agent for Overhauser-enhanced MRI, J. Biomater. Sci. Polym. Ed., 25, 1425-1439 (2014)
  4. Takuro Niidome, Hisayo Yamauchi, Kayo Takahashi, Kenshiro Naoyama, Kazuto Watanabe, Takeshi Mori, Yoshiki Katayama, Hydrophobic cavity formed by oligopeptide for doxorubicin delivery based on dendritic poly(L-lysine), J. Biomater. Sci. Polym. Ed., 25, 1362-1373 (2014)
  5. Nicholas A. Peppas, Ruth Duncan, Gary Wnek, Allan Hoffman, Guang Hui Gao, SungWan Kim, Doo Sung Lee, Michael Hadjiargyrou, ElkaTouitou, Denize Ainbinder, Russell Mumper, Alain Rolland, Takuro Niidome, Vinod Labhasetawar, Shi Liu, Guangyuan Zhou, Yubin Huang, Zhigang Xie, Xiabin Jjing, Noemi Csaba, Maria Jose Alonso, Omar Ali, David J. Mooney, Peter Lönn, Steven F. Dowdy, Si-Shen Feng, Jinming Gao, Eun Seong Lee, Kun Na, You Han Bae, Gaylen M. Zentner, Hyesung Kim, Hyuk Sang Yoo, Masamichi Nakayama, Teruo Okano, Zi-Xian Liao, Er-Yuan Chuang, Chun-Wen Hsiao, Hsing-Wen Sung, Horacio Cabral, Kazunori Kataoka, Praful R. Nair, Dennis Discher, Samir Mitragotri, Highly cited research articles in Journal of Controlled Release: Commentaries and perspectives by authors, J. Controlled Release, 190, 48-50 (2014)
  6. Takuro Niidome, Nobukatsu Chijiiwa, Toshihide Yamsaki, Kenichi Yamada, Takeshi Mori, Tatsuya Naganuma, Hideo Utsumi, Kazuhiro Ichikawa, Yoshiki Katayama, Change in Overhauser effect-enhaced MRI signal in response to uPA highly expressing in tumor, Chem. Lett., 43, 999-1001 (2014)
  7. Yuki Otsubo, Hiromu Ikeda, Jumpei Kamimoto, Takuro Niidome, Takeshi Mori, Yoshiki Katayama, A rapid and quantitative detection of cellular protein kinase activity based on MALDI-TOF-MS, Chem. Lett., 43, 658-660 (2014)
  8. Takanobu Nobori, Shuji Shiosaki, Tekashi Mori, Riki Toita, Chan Wo Kim, Yuta Nakamura, Akihiro Kishimura, Takuro Niidome, Yoshiki Katayama, Fluorescent polyion complex nanoparticle that incorporates an internal standard for quantitative analysis of protein kinase activity, Bioconjug Chem., 25, 869-872 (2014)
  9. Kyohei Tobinaga, Cuicui Li, Masafumi Takeo, Masayoshi Matsuda, Hiroko Nagai, Takuro Niidome, Tatsuhiro Yamamoto, Akihiro Kishimura, Takeshi Mori, Yoshiki Katayama, Corresponding author contact information, E-mail the corresponding author, Rapid and serum-insensitive endocytotic delivery of proteins using biotinylated polymers attached via multivalent hydrophobic anchors, J. Controlled Release, 177, 27-33 (2014)
  10. Guo Xian Zhao, Hironao Tanaka, Chan Wo Kim, Kai Li, Daiki Funamoto, Takanobu Nobori, Yuta Nakamura, Takuro Niidome, Akihiro Kishimura, Takeshi Mori, Yoshiki Katayama, Histidinylated poly-L-lysine-based vectors for cancer-specific gene expression via enhancing the endosomal escape, J. Biomater. Sci. Polym. Ed., 25, 519-534 (2014)
  11. Nobuhito Hamano, Yoichi Negishi, Kyohei Takatori, Yoko Endo-Takahashi, Ryo Suzuki, Kazuo Maruyama, Takuro Niidome, Yukihiko Aramaki, Combination of bubble liposomes and high-intensity focused ultrasound (HIFU) enhanced antitumor effect by tumor ablation, Biol. Pharm. Bull., 37, 174-177 (2014)
  12. Masanori Fujii, Naotoshi Nakashima, Takuro Niidome, Yasuro Niidome, Imaging mass spectrometry of intravenously injected gold nanorods in mice, Chem. Lett. 43, 131-133 (2014)

2013

  1. Hiromu Ikeda, Junpei Kamimoto, Tatsuhiro Yamamoto, Akito Hata, Yuki Otsubo, Takuro Niidome, Masao Fukushima, Takeshi Mori, Yoshiki Katayama, A peptide microarray fabricated on a non-fouling phosphatidylcholine-polymer-coated surface for a high-fidelity analysis of a cellular kinome, Curr. Med. Chem., 20, 4419-4425 (2013)
  2. Satoshi Kushio, Akira Tsuchiya, Yuta Nakamura, Takanobu Nobori, Chan Woo Kim, Guo Xi Zhao, Taiki Funamoto, Eun Kyung Lee, Takuro Niidome, Takeshi Mori, Yoshiki Katayama, Cancer-specific gene carriers responding to cancer microenvironment: acidosis and hyper-activated protein kinases, Biomed. Eng-App. Bas. C., 25, 1340005 (2013)
  3. Hengmin Tang, Hiroaki Kobayashi, Yasuro Niidome, Takeshi Mori, Yoshiki Katayama, Takuro Niidome, CW/pulsed NIR irradiation of gold nanorods: effect on transdermal protein delivery mediated by photothermal ablation, J. Controlled Release, 171, 178-183 (2013)
  4. Yasuyuki Akiyama, Yasuro Niidome, Takeshi Mori, Yoshiki Katayama, Takuro Niidome, PEG-silica-modified gold nanorods that retain their optical properties in tumor tissues, J. Biomater. Sci.-Polym. Ed., 24, 2071-2080 (2013)
  5. Kengo Wakigawa, Akinaga Gohda, Sunao Fukushima, Takeshi Mori, Takuro Niidomea, Yoshiki Katayama, Rapid and selective determination of free chlorine in aqueous solution using electrophilic addition to styrene by gas chromatography/mass spectrometry, Talanta, 203, 81-85 (2013)
  6. Jeong-Hun Kang, Takeshi Mori, Hirotaro Kitazaki, Takuro Niidome, Koichi Takayama, Yoichi Nakanishi, Yoshiki Katayama, Kinase activity of protein kinase Calpha in serum as a diagnostic biomarker of human lung cancer, Anticancer Res., 33, 485-488 (2013)
  7. Chan Woo Kim, Riki Toita, Jeong-Hun Kang, Kai Li, Eun Kyung Lee, Guo Xi Zhao, Daiki Funamoto, Takanobu Nobori, Yuta Nakamura, Takeshi Mori, Takuro Niidome, Yoshiki Katayama, Stabilization of cancer-specific gene carrier via hydrophobic interaction for a clear-cut response to cancer signaling, J. Controlled Release, 170, 469-476 (2013)
  8. Yuta Nakamura, Chan Woo Kim, Akira Tsuchiya, Satoshi Kushio, Takanobu Nobori, Kai Li, Eun Kyung Lee, Guo Xi Zhao, Daiki Funamoto, Takuro Niidome, Takeshi Mori, Yoshiki Katayama, Branched polyethylenimine-based PKCα-responsive gene carriers, J. Biomater. Sci.-Polym. Ed., 24, 1858-1868 (2013)
  9. Shujiro Shiosaki, Takanobu Nobori, Takeshi Mori, Riki Toita, Yuta Nakamura, Chan Woo Kim, Tatsuhiro Yamamoto, Takuro Niidome, Yoshiki Katayama, A protein kinase assay based on FRET between quantum dots and fluorescently-labeled peptides, Chem. Commun, 49, 5592-5594 (2013)
  10. Yuki Sakamura, Moemi Yoshiura, Hengmin Tang, Takeshi Mori, Yoshiki Katayama, Takuro Niidome, Thermal enhancement of gene transfection in tumor cells mediated by the photothermal effect of gold nanorods, Chem. Lett. 42, 767-768 (2013)
  11. Masafumi Takeo, Takeshi Mori, Takuro Niidome, Shinich Sawada, Kazunari Akiyoshi, Yoshiki Katayama, A polyion complex nanogel, J. Collod. Interf. Sci., 390, 78-84 (2013)

2012

  1. Ryohsuke Kurihara, Dakrong Pissuwan, Takeshi Mori, Yoshiki Katayama, Takuro Niidome, Biodistribution and tumor localization of PEG-modified dendritic poly(L-lysine) oligonucleotide complexes, J. Biomater. Sci.-Polym. Ed., 23, 2369-2380 (2012)
  2. Yasuyuki Akiyama, Takeshi Mori, Yoshiki Katayama, Takuro Niidome, Conversion of rod-shaped gold nanoparticles to spherical forms and their effect on biodistribution in tumor-bearing mice, Nanoscale Res. Lett., 7, 565 (2012)
  3. Riki Toita, Jeong-Hun Kang, Tetsuro Tomiyama, Chan Woo Kim, Shujiro Shiosaki, Takuro Niidome, Takeshi Mori, Yoshiki Katayama, Gene carrier showing all-or-none response to cancer cell signaling, J. Am. Chem. Soc., 134, 15410-15417 (2012)
  4. Hidetoshi Arima, Ayumi Yoshimatsu, Haruna Ikeda, Ayumu Ohyama, Keiichi Motoyama, Taishi Higashi, Akira Tsuchiya, Takuro Niidome, Yoshiki Katayama, Kenjiro Hattori, Tomoko Takeuchi, Folate-PEG-appended dendrimer conjugate with α-cyclodextrin as a novel cancer cell-selective siRNA delivery carrier, Mol. Pharmaceutics, 9, 2591-2604 (2012)
  5. Dakrong Pissuwan, Takuro Niidome, Gold nanoparticles for the development of transdermal delivery systems, ACS Symposium Series, Functional Nanoparticles for Bioanalysis, Nanomedicine and Bioelectronic Devices, Volume 2, Chapter 5, 69–80 (2012)
  6. Yoshiro Tahara, Takeshi Kaneko, Riki Toita, Chiharu Yoshiyama, Takuya Kitaoka, Takuro Niidome, Yoshiki Katayama, Noriho Kamiya, Masahiro Goto, A novel double-coating carrier produced by solid-in-oil and solid-in-water nanodispersion technology for delivery of genes and proteins into cells, J. Controlled Release, 161, 713-721 (2012)
  7. Keisuke Nose, Dakrong Pissuwan, Masahiro Goto, Yoshiki Katayama, Takuro Niidome, Gold nanorods in an oil-base formulation for transdermal treatment of Type 1 diabetes in mice, Nanoscale, 4, 3776-3780 (2012)
  8. Hiromitsu Fukushima, Shuji Yamashita, Takeshi Mori, Yoshiki Katayama, Takuro Niidome, Sequential release of single-stranded DNAs from gold nanorods triggered by near-infrared light irradiation, Chem. Lett., 41, 711-712, (2012)
  9. Riki Toita, Takeshi Mori, Yuki Naritomi, Jeong-Hun Kang, Shujiro Shiosaki, Takuro Niidome, Yoshiki Katayama, Fluorometric detection of protein kinase Calpha activity based on phosphorylation-induced dissociation of a polyion complex, Anal. Biochem., 424, 130-136 (2012)
  10. Akira Tsuchiya, Yuki Naritomi, Satoshi Kushio, Jeong-Hun Kang, Masaharu Murata, Makoto Hashizume, Takeshi Mori, Takuro Niidome, Yoshiki Katayama, Improvement in the colloidal stability of protein kinase-responsive polyplexes by PEG modification, J. Biomed. Mater. Res. Part A, 100, 1136-1141 (2012)
  11. Hiroyuki Tanaka, Takeshi Mori, Takuro Niidome, Yoshiki Katayama, Creating a unique environment for selecting reactive enzymes with DNA: “Sticky” binding of oligocation-grafted polymers to DNA, Bioorg. Med. Chem., 20, 1346-1353 (2012)
  12. Hirotaro Kitazaki, Takeshi Mori, Jeong-Hun Kang, Takuro Niidome, Masaharu Murata, Makoto Hashizume, Yoshiki Katayama, A colorimetric assay of protein kinase activity based on peptide-induced coagulation of gold nanorods, Coll. Surf. B, 99, 7-11 (2012)
  13. Akira Tsuchiya, Daisuke Asai, Jeong-Hun Kang, Takeshi Mori, Takuro Niidome, Yoshiki Katayama, Correlation between phosphorylation ratios by MALDI-TOF MS analysis and radioactivities by radioactive assay, Anal. Biochem., 15, 773-775 (2012)

2011

  1. Shuji Yamashita, Hiromitsu Fukushima, Yasuro Niidome, Takeshi Mori, Yoshiki Katayama, Takuro Niidome, Controlled-release system mediated by a retro Diels-Alder reaction induced by the photothermal effect of gold nanorods, Langmuir 27, 14621-14626 (2011)
  2. Haruka Koga, Riki Toita, Takeshi Mori, Tetsuro Tomiyama, Jeong-Hun Kang, Takuro Niidome, Yoshiki Katayama, Fluorescent nanoparticles consisting of lipopeptides and fluorescein-modified polyanions for monitoring of protein kinase activity, Bioconjugate Chem., 22, 1526-1534 (2011)
  3. Jeong-Hun Kang, Daisuke Asai, Akira Tsuchiya, Takeshi Mori, Takuro Niidome, Yoshiki Katayama, Peptide substrates for Rho-associated kinase 2 (Rho-kinase 2/ROCK2), PLoS ONE, 6, e22699 (2011)
  4. Tetsuro Tomiyama, Riki Toita, Jeong-Hun Kang, Haruka Koga, Shujiro Shiosaki, Takeshi Mori, Takuro Niidome, Yoshiki Katayama, Effect of the introduction of condroitin sulfate into polymer-peptide conjugate responding to intracellular signals, Nanoscale Res. Lett., 6, 532 (2011)
  5. Yoji Asami, Jun Oishi, Hirotaro Kitazaki, Jumpei Kamimoto, Jeong-Hun Kang, Takuro Niidome, Takeshi Mori, Yoshiki Katayama, A simple set-and-mix assay for screening of protein kinase inhibitors in cell lysates, Anal. Biochem., 418, 44-49 (2011)
  6. Shujiro Shiosaki, Masanori Kuramoto, Riki Toita, Takeshi Mori, Takuro Niidome, Yoshiki Katayama, A hydrophilic polymer grafted with a histone tail peptide represents an artificial gene regulator activated by a histone acetyltransferase, Bioorg. Med. Chem., 19, 4101-41405 (2011)
  7. Akira Tsuchiya, Jeong-Hun Kang, Daisuke Asai, Takeshi Mori, Takuro Niidome, Yoshiki Katayama, Transgene regulation system responding to Rho associated coiled-coil kinase (ROCK) activation, J. Controlled Release, 155, 40-46 (2011)
  8. Shuji Yamashita, Hiromitsu Fukushima, Yasuyuki Akiyama, Yasuro Niidome, Takeshi Mori, Yoshiki Katayama, Takuro Niidome, Controlled-release system of single-stranded DNA triggered by the photothermal effect of gold nanorods and its in vivo application, Bioorg. Med. Chem., 19, 2130-2135 (2011)
  9. Takashi Shimomura, Xiaoming Han, Akito Hata, Takuro Niidome, Takeshi Mori, Yoshiki Katayama, Optimization of peptide density on microarray surface for quantitative phosphoproteome, Anal. Sci., 27, 13-17 (2011)
  10. Dakrong Pissuwan, Keisuke Nose, Ryohsuke Kurihara, Kenji Kaneko, Yoshiro Tahara, Noriho Kamiya, Masahiro Goto, Yoshiki Katayama, Takuro Niidome, A solid-in-oil dispersion of gold nanorods can enhance trandermal protein delivery and skin vaccination, Small, 17, 215-221 (2011)
  11. Dakrong Pissuwan, Takuro Niidome, Michael B. Cortie, The forthcoming applications of gold nanoparticles in drug and gene delivery systems, J. Controlled Release, 149, 65-71 (2011)

2010

  1. Atsushi Shiotani, Yasuyuki Akiyama, Takahito Kawano, Yasuro Niidome, Takeshi Mori, Yoshiki Katayama, Takuro Niidome, Active accumulation of gold nanorods in tumor in response to near-infrared laser irradiation, Bioconjugate Chem., 21, 2049-2054 (2010)
  2. Xiaoming Han, Tatsuhiko Sonoda, Takeshi Mori, Go Yamanouchi, Takayuki Yamaji, Syuhei Shigaki, Takuro Niidome, Yoshiki Katayama, Protein kinase substrate profiling with a high-density peptide microarray, Comb. Chem. High Throughput Screen. 13, 777-789 (2010)
  3. Tetsuro Tomiyama, Riki Toita, Jeong-Hun Kang, Daisuke Asai, Shujiro Shiosaki, Takeshi Mori, Takuro Niidome, Yoshiki Katayama, Tumor therapy by gene regulation system responding to cellular signal, J. Controlled Release, 148, 101-105 (2010)
  4. Jun Oishi, Joohee Jung, Akira Tsuchiya, Riki Toita, Jeong-Hun Kang, Takeshi Mori, Takuro Niidome, Katsuyuki Tanizawa, Shun'ichi Kuroda, Yoshiki Katayama, A gene delivery system specific for hepatoma cells and an intracellular kinase signal based on human liver-specific bionanocapsules and signal-responsive artificial polymer, Int. J. Pharm., 396, 174-178 (2010)
  5. Takeshi Mori, Suguru Beppu, Mohamed Berber, Hiroronori Mori, Takumi Makimura, Ayako Tsukamoto, Keiji Minagawa, Tomohiro Hirano, Masami Tanaka, Takuro Niidome, Yoshiki Katayama, Tatsuya Hirano, Yasushi Maeda, Design of temperature-responsive α,α-disubstituted vinyl polymers with enhanced hysteresis, Langmuir 26, 9224-9232 (2010)
  6. Takuro Niidome, Akira Ohga, Yasuyuki Akiyama, Kazuto Watanabe, Yasuro Niidome, Takeshi Mori, Yoshiki Katayama, Controlled release of PEG chain from gold nanorods: targeted delivery to tumor, Bioorg. Med. Chem., 18, 4453-4458 (2010)
  7. Joeng-Hun Kang, Jun Oishi, Jong-Hwan Kim, Moeko Ijuin, Riki Toita, Byungdug Jun, Daisuke Asai, Takeshi Mori, Takuro Niidome, Katsuyuki Tanizawa, Shun'ichi Kuroda, Yoshiki Katayama, Hepatoma-targeted gene delivery using a tumor cell-specific gene regulation system combined with a human liver cell-specific bionanocapsule, Nanomedicine 6, 583-589 (2010)
  8. Mohamed Berber, Hironori Mori, Inas Hafez, Keiji Minagawa, Masami Tanaka, Takuro Niidome, Atsushi Maruyama, Tomohiro Hirano, Takeshi Mori, Yoshiki Katayama, Yasushi Maeda, Unusually large hysteresis of temperature-responsive poly(N-ethyl-2-propionamidoacrylamide) studied by microcalorimetry and FT-IR, J. Phys. Chem., 114, 7784-7790 (2010)
  9. Kohei Shiba, Takuro Niidome, Etsuko Katoh, Hongyu Xiang, Lu Han, Takeshi Mori, Yoshiki Katayama, Polydispersity as a parameter for indicating the thermal stability of proteins by dynamic light scattering, Anal. Sci. 26, 659-663 (2010)
  10. Yuko Sato, Kenji Kawamura, Takuro Niidome, Yoshiki Katayama, Characterization of gene expression regulation using D-RECS polymer by enzymatic reaction for an effective design of enzyme-responsive gene regulator, J. Controlled Release, 143, 344-349 (2010)
  11. Jeong-Hun Kang, Yoji Asami, Masaharu Murata, Hirotaro Kitazaki, Noriaki Sadanaga, Eriko Tokunaga, Satoko Shiotani, Satoko Okada, Yoshihiko Maehara, Takuro Niidome, Makoto Hashizume, Takeshi Mori, Yoshiki Katayama, Gold nanoparticle-based colorimetric assay for cancer diagnosis, Biosens. Bioelectron., 25, 1869-1874 (2010)
  12. Daisuke Asai, Masanori Kuramoto, Yoko Shoji, Kota Bae Kodama, Jeong-Hun Kagng, Kenji Kawamura, Hiroshi Miyoshi, Takeshi Mori, Takuro Niidome, Hideki Nakashima, Yoshiki Katayama, Specific transgene expression in HIV-infected cells using protease-cleavable transcription regulator, J. Controlled Release 141, 52-61 (2010)

2009

  1. Kazuki Inamori, Motoki Kyo, Kazuki Matsukawa, Yukuke Inoue, Tatsuhiko Sonoda, Takeshi Mori, Takuro Niidome, Yoshiki Katayama, Establishment of screening system toward discovery of kinase inhibitors using label-free on-chip phosphorylation assays, BioSystems, 97, 179-185 (2009)
  2. Tetsuro Tomiyama, Jeong-Hun Kang, Riki Toita, Takuro Niidome, Yoshiki Katayama, Protein kinase Cα-responsive polymeric carrier: Its application for gene delivery into human cancers, Cancer Sci., 100, 1532-1536 (2009)
  3. Shinichi Kuriyamaa, Yasushi Taguchi, Kazuto Watanabe, Kanako Nishimuraa, Kazutoshi Yanagibashi, Yoshiki Katayama, Takuro Niidome, Stability of DNA/Td3717 complexes for gene transfection, defined by the size and polydispersity of the complex, Bioorg. Med. Chem., 17, 7643-7646 (2009)
  4. Riki Toita, Jeong-Hun Kang, Jong-Hwan Kim, Tetsuro Tomiyama, Takeshi Mori, Takuro Niidome, Byungdug Jun, Yoshiki Katayama, Protein kinase Cα-specific peptide substrate graft-type copolymer for cancer cell-specific gene regulation systems, J. Controlled Release, 139, 133-139 (2009)
  5. Tomoaki Kurosaki, Reiko Kishikawa, Megumi Matsumoto, Yukinobu Kodama, Tomoyuki Hamamoto, Hideto To, Takuro Niidome, Kozo Takayama, Takashi Kitahara, Hitoshi Sasaki, Pulmonary gene delivery of hybrid vector, lipopolyplex containing N-lauroylsarcosine, via the systemic route, J. Controlled Release, 136, 213-219 (2009)
  6. Jeong-Hun Kang, Takuro Niidome, Yoshiki Katayama, Role of estrogenic compounds (diethylstibestrol, 17beta－estradiol, and bisphenol A) in the phosphorylation of substrate by protein kinase Calpha, J. Biochem. Mol. Toxicol., 23, 318-323 (2009)
  7. Kazuto Watanabe, Mariko Harada-Shiba, Akira Suzuki, Risa Gokuden, Ryohsuke Kurihara, Yusuke Sugao, Takeshi Mori, Yoshiki Katayama, Takuro Niidome, In vivo siRNA delivery with dendritic poly(L-lysine) for the treatment of hypercholesterolemia, Molecular BioSystems, 5, 1306 - 1310 (2009)
  8. Jeong-Hun Kang, Riki Toita, Tetsuro Tomiyama, Jun Oishi, Daisuke Asai, Takeshi Mori, Takuro Niidome, Yoshiki Katayama, Cellular signal-specific peptide substrate is essential for the gene delivery system responding to cellular signals, Bioorg. Med. Chem. Lett., 19, 6082-6086 (2009)
  9. Yasuyuki Akiyama, Takeshi Mori, Yoshiki Katayama, Takuro Niidome, The effects of PEG grafting level and injection dose on gold nanorod biodistribution in tumor-bearing mice, J. Controlled Release. 139, 81-84 (2009)
  10. Yusuke Sugao, Kazuto Watanabe, Yuriko Higuchi, Ryohsuke Kurihara, Shigeru Kawakami, Mitsuru Hashida, Yoshiki Katayama, Takuro Niidome, NFkB decoy delivery using dendritic poly(L-lysine) for treatment of endotoxin-induced hepatitis in mice, Bioorg. Med. Chem., 17, 4990-4995 (2009)
  11. Tomoko Hashimoto, Yoichi Tachibana, Hisae Nozaki, Osam Mazda, Takuro Niidome, Akira Murakami, Tetsuji Yamaoka, Intracellular enzyme-responsive fragmentation of nonviral gene carriers leads to polyplex destabilization and enhanced transgene expression, Chem. Lett., 38, 718-719 (2009)
  12. Shinichi Kuriyama, Kanako Nishimura, Yasushi Taguchi, Kazutoshi Yanagibashi, Yoshiki Katayama, Takuro Niidome, Phosphatidylserine-selective conformational change of α-helix peptide, Td3717, and its ability to transfect cancer cells, Chem. Lett., 38, 684-685 (2009)
  13. Daisuke Asai, Akira Tsuchiya,Jeong-Hun Kang, Kenji Kawamura, Jun Oishi, Takeshi Mori, Takuro Niidome, Yoko Shoji, Hideki Nakashima, Yoshiki Katayama, Inflammatory cell-specific gene regulation system responding to Ikappa-B kinase beta activation, J. Gene Med., 11, 624-632 (2009)
  14. Takeshi Mori, Go Yamanouchi, Xiaoming Han, Yusuke Inoue, Syuhei Shigaki, Takayuki Yamaji, Tatsuhiko Sonoda, Kei Yasui, Hisato Hayashi, Takuro Niidome, Yoshiki Katayama, Signal-to-noise ratio improvement of peptide microarrays by using hyperbranched-polymer materials, J. Appl. Phys., 105, 102020 (2009)
  15. Xiaoming Han, Go Yamanouchi, Takeshi Mori, Jeong-Hun Kang, Takuro Niidome, Yoshiki Katayama, Monitoring protein kinase activity in cell lysates using a high density peptide microarray, J. Biomol. Screen. 14, 256-262 (2009)
  16. Takuro Niidome, Yasuyuki Akiyama, Masato Yamagata, Takahito Kawano, Takeshi Mori, Yasuro Niidome, Yoshiki Katayama, Poly(ethylene glycol)-modified gold nanorods as a photothermal nanodevice for hyperthermia, J. Biomater. Sci.-Polym. Ed., 20, 1203-1215 (2009)
  17. Kentaro Sao, Masaharu Murata, Yuri Fujisaki, Kaori Umezaki, Takeshi Mori, Takuro Niidome, Yoshiki Katayama, Makoto Hashizume, A novel protease activity assay using a protease-responsive chaperone protein, Biochem. Biophys. Res. Commun., 383, 293-297 (2009)
  18. Kenji Kawamura, Masanori Kuramoto, Takeshi Mori, Riki Toita, Jun Oishi, Yuko Sato, Jeoung-Hun Kang, Daisuke Asai, Takuro Niidome, Yoshiki Katayama, Molecularmechanism of Caspase-3-induced gene expression of polyplexes formed polycations grafted with cationic substrate peptides, J. Biomater. Sci. Polym. Ed., 20, 967-980 (2009).
  19. Tomoaki Kurosaki, Takashi Kitahara, Shintaro Fumoto, Koyo Nishida, Junzo Nakamura, Takuro Niidome, Yukinobu Kodama, Hiroo Nakagawa, Hideto To, Hitoshi Sasaki, Ternary complexes of pDNA, polyethylenimine, and gamma-polyglutamic acid for gene delivery systems, Biomaterials, 30, 2846-2853 (2009)
  20. Shuji Yamashita, Yasuro Niidome, Yoshiki Katayama, Takuro Niidome, Photochemical reaction of poly(ethylene glycol) on gold nanorods induced by near infrared pulsed-laser irradiation, Chem. Lett., 38. 226-227 (2009)
  21. Ryuhei Nishiyabu, Nozomi Hashimoto, Ten Cho, Kazuto Watanabe, Takefumi Yasunaga, Ayataka Endo, Kenji Kaneko, Takuro Niidome, Masaharu Murata, Chihaya Adachi, Yoshiki Katayama, Makoto Hashizume, Nobuo Kimizuka, Nanoparticles of adaptive supramolecular networks self-assembled from nucleotides and lanthanide ions, J. Am. Chem. Soc., 131. 215-218 (2009)
  22. Takahito Kawano, Yasuro Niidome, Takeshi Mori, Yoshiki Katayama, Takuro Niidome, PNIPAM gel-coated gold nanorods for targeted delivery responding to a near-infrared laser, Bioconjugate Chem., 20. 209-212 (2009)
  23. Daisuke Asai, Jeong-Hun Kang, Riki Toita, Akira Tsuchiya, Takuro Niidome, Hideki Nakashima, Yoshiki Katayama, Regulation of transgene expression in tumor cells by exploiting endogenous intracellular signals, Nanoscale Res. Lett. 4, 229-233 (2009)
  24. Takeshi Mori, Tomohiro Hirano, Atsushi Maruyama, Yoshiki Katayama, Takuro Niidome, Yoichi Bando, Koichi Ute, Shinji Takaku, Yasushi Maeda, Syndiotactic poly(N-n-propylacrylamide) shows highly cooperative phase transition, Langmuir, 25, 48-50 (2009)
  25. Takuro Niidome, Kosuke Yakumaru, Atsushi Shiotani, Shuzo Yamashita, Yoshiki Katayama, Gene transfer into cells from solid surfaces and its application to in vivo systems, Chem. Lett., 38, 36-37 (2009)
  26. Kentaro Sao, Masaharu Murata, Kaori Umezaki, Yuri Fujisaki, Takeshi Mori, Takuro Niidome, Yoshiki Katayama, Makoto Hashizume, Molecular design of protein-based nanocapsules for stimulus-responsive characteristics, Bioorg. Med. Chem., 17, 85-93 (2009)
  27. Jeong-Hun Kang, Takeshi Mori, Takuro Niidome, Yoshiki Katayama, A syngeneic hepatocellular carcinoma model rapidly and simply prepared using a hydrodynamics-based procedure, Vet. J., 181, 336-339 (2009)

2008

  1. Shinichi Kuriyama, Yasushi Taguchi, Kanako Nishimura, Kazutoshi Yanagibashi, Yoshiki Katayama, Takuro Niidoime, Improvement of peptide vectors for gene delivery with active targeting profiles for phosphatidylserine, J. Peptide Sci., 15, 114-119 (2008)
  2. Jeong-Hun Kang, Daisuke Asai, Jong-Hwan Kim, Takeshi Mori, Riki Toita, Tetsuro Tomiyama, Yoji Asami, Jun Oishi, Yuko T. Sato, Takuro Niidome, Byungdug Jun, Hideki Nakashima, Yoshiki Katayama, Design of polymeric carriers for cancer-specific gene targeting: Utilization of abnormal protein kinase Cα activation in cancer cells,J. Am. Chem. Soc., 130, 14906-14907 (2008)
  3. Jun Oishi, Yoji Asami, Takeshi Mori, Jeong-Hun Kang, Takuro Niidome, Yoshiki Katayama, Colorimetric enzymatic activity assay based on "non-crosslinking aggregation" of gold nanoparticles induced by adsorption of substrate peptides, Biomacromolecules, 9, 2301-2308 (2008)
  4. Daisuke Asai, Kota Bae Kodama, Yoko Shoji, Hideki Nakashima, Kenji Kawamura, Jun Oishi, Masanori Kuramoto, Takuro Niidome, Yoshiki Katayama, Drug delivery system based on resonses to an HIV infectious signal, Medicinal Chem., 4, 386-391 (2008)
  5. Jeong-Hun Kang,　Masanori Kuramoto, Akira Tsuchiya, Riki Toita, Daisuke Asai, Yuko T. Sato, Takeshi Mori, Takuro Niidome, Yoshiki Katayama, Correlation between phosphorylation ratios by MALDI-TOF MS analysis and enzyme kinetics, Eur. J. Mass Spectrom., 14, 261-265 (2008)
  6. Yukichi Horiguchi, Shuji Yamashita, Takuro Niidome, Naotoshi Nakashima, Yasuro Niidome, Photoinduced release of oligonucleotide-conjugated silica-coated gold nanorods accompanied by moderate morphological changes, Chem. Lett., 265, 281-288 (2008)
  7. Takuro Niidome, Yasuyuki Akiyama, Kohei Shimoda, Takahito Kawano, Takeshi Mori, Yoshiki Katayama, and Yasuro Niidome, In vivo monitoring of intravenously injected gold nanorods using near-infrared light, Small, 4, 1001-1007 (2008)
  8. Jeong-Hun Kang, Daisuke Asai, Satoshi Yamada, Toita Riki, Jun Oishi, Takeshi Mori, Takuro Niidome, Yoshiki Katayama, A short peptide is a protein kinase C (PKC)α-specific substrate, Proteomics, 8, 2006-2011 (2008)
  9. Jeong-Hun Kang, Riki Toita, Takuro Niidome, Yoshiki Katayama, Effective delivery of DNA into tumor cells and tissues by electroporation of polymer-DNA complex, Cancer Lett., 265, 281-288 (2008)
  10. Kenjiro Ikuta, Takeshi Mori, Tatsuhiro Yamamoto, Takuro Niidome, Hiroaki Shimokawa, Yoshiki Katayama, Development of polymeric drug delivery system for recognizing vascular endothelial dysfunction, Bioorg. Med. Chem., 16, 2811-2818 (2008)
  11. Takeshi Mori, Kazuki Inamori, Yusuke Inoue, Xiaoming Han, Go Yamanouchi, Takuro Niidome, Yoshiki Katayama, Evaluation of protein kinase activities of cell lysates using peptide microarrays based on SPR imaging, Anal. Biochem., 375, 223-231 (2008)
  12. Yusuke Inoue, Takeshi Mori, Go Yamanouchi, Xiaoming Han, Tatsuhiko Sonoda, Takuro Niidome, Yoshiki Katayama, Surface plasmon resonance imaging measurements of caspase reactions on peptide microarrays, Anal. Biochem., 375, 147-149 (2008)
  13. Hironobu Takahashi, Takuro Niidome, Takahito Kawano, Yasuro Niidome, Sunao Yamada, Surface modification of gold nanorods using layer-by-layer technique for cellular uptake, J. Nanopart. Res., 10, 221-228 (2008)
  14. Jun Oishi, Xiaoming Han, Jeong-Hun Kang, Yoji Asami, Takeshi Mori, Takuro Niidome, Yoshiki Katayama, High-throughput colorimetric detection of tyrosine kinase inhibitors based on the aggregation of gold nanoparticles, Anal. Biochem., 373, 161-163 (2008)
  15. Xiaoming Han, Syuhei Shigaki, Takayuki Yamaji, Go Yamanouchi, Takeshi Mori, Takuro Niidome, Yoshiki Katayama, A quantitative peptide array for evaluation of protein kinase activity, Anal. Biochem., 372, 106-115 (2008)
  16. Yusuke Inoue, Ryosuke Kurihara, Akiko Tsuchida, Mino Hasegawa, Takeyuki Nagashima, Takeshi Mori, Takuro Niidome, Yoshiki Katayama, Osamu Okitsu, Efficient delivery of siRNA using dendritic poly(L-lysine) for loss-of-function analysis, J. Controlled Release, 126, 59-66 (2008)

2007

  1. Jeong-Hun Kang, Daisuke Asai, Jun Oishi, Kenji Kawamura, Riki Toita, Yuhua Jiang, Takeshi Mori, Takuro Niidome, Yoshiki Katayama, Role of plasma as activator and cofactor in phosphorylation by protein kinase C , Cell Biochem. Funct. 26, 70-75 (2007)
  2. Jeong-Hun Kang, Riki Toita, Jun Oishi, Takuro Niidome, Yoshiki Katayama, Effect of the addition of diammonium citrate to alpha-cyano-4-hydroxycinnamic acid (CHCA) matrix for the detection of phosphorylated peptide in phosphorylation reactions using cell and tissue lysates, J. Am. Soc. Mass Spectrom., 18, 1925－1931 (2007)
  3. Yukichi Horiguchi, Takuro Niidome, Sunao Yamada, Naotoshi Nakashima, Yasuro Niidome, Expression of plasmid DNA released from DNA conjugates of gold nanorods, Chem. Lett., 36, 952-953, (2007)
  4. Jun Oishi, Yoji Asami, Takeshi Mori, Jeong-Hun Kang, Miharu Tanabe, Takuro Niidome, Yoshiki Katayama, Measurement of homogeneous kinase activityfor cell lysates based on the aggregation of gold nanoparticles, ChemBioChem, 8, 875-879, (2007)
  5. Takeshi Mori, Suguru Beppu, Isao Fukushima, Toru Kobayashi, Kenji Minagawa, Masami Tanaka, Takuro Niidome, Yoshiki Katayama, Temperature-responsive Poly(dehydroalanine)s: Diversifying Phase Transition Temperatures Utilizing alpha,alpha-Disubstituted Motif, Chem. Lett., 36, 334-335 (2007)
  6. Takeshi Mori, Shiro Yasutake, Hideki Inoue, Keiji Minagawa, Masami Tanaka, Takuro Niidome, Yoshiki Katayama, "Threading" of beta-Sheet Peptides via Radical Polymerization, Biomacromolecules, 8, 318-321 (2007)
  7. Shuhei Shigaki, Takayuki Yamaji, Xiaoming Han, Go Yamanouchi, Tatsuhiko Sonoda, Osamu Okitsu, Takeshi Mori, Takuro Niidome, Yoshiki Katayama, A peptide microarray for the detection of protein kinase activity in cell lysate, Anal. Sci., 23, 271-275 (2007)
  8. Atsushi Shiotani, Takeshi Mori, Takuro Niidome, Yasuro Niidome, Yoshiki Katayama, Stable incorporation of gold nanorods into N-isopropylacrylamide hydrogels and their rapid shrinkage induced by near-IR laser irradiation, Langmuir, 23, 4012-4018 (2007)
  9. Takayuki Iida, Takeshi Mori, Yoshiki Katayama, Takuro Niidome, Overall interaction of cytosolic proteins with the PEI/DNA complex, J. Controlled Release, 118, 364-369 (2007)
  10. Jeong-Hun Kang, Aishan Han, Shuhei Shigaki, Jun Oishi, Kenji Kawamura, Riki Toita, Xiao Ming Han, Takeshi Mori, Takuro Niidome, Yoshiki Katayama, Mass-tag technology responding to intracellular signals as a novel assay system for the diagnosis of tumor, J. Am. Soc. Mass Spectrom. 18, 106-112 (2007)
  11. Masato Yamagata, Takahito Kawano, Kouhei Shiba, Takeshi Mori, Yoshiki Katayama, Takuro Niidome, Structural advantage of dendritic poly(L-lysine) for gene delivery into cells, Bioorg. Med. Chem., 15, 526-532 (2007)
  12. Jeong-Hun Kang, Yuhua Jiang, Riki Toita, Jun Oishi, Kenji Kawamura, Aishan Han, Takeshi Mori, Takuro Niidome, Masami Ishida, Kenji Tatematsu, Katsuyuki Tanizawa, Yoshiki Katayama, Phosphorylation of Rho-associated kinase (Rho-kinase/ROCK/ROK) substrates by protein kinases A and C, Biochimie, 89, 39-47 (2007)

2006

  1. Tatsuya Okuda, Shigeru Kawakami, Naomi Akimoto, Takuro Niidome, Fumiyoshi Yamashita, Mitsuru Hashida, PEGylated lysine dendrimers for tumor-telective targeting after intravenous injection in tumor-bearing mice, J. Controlled Release, 116, 330-336 (2006)
  2. Hironobu Takahashi, Takuro Niidome, Ayuko Nariai, Yasuro Niidome, Sunao Yamada, Photothermal reshaping of gold nanorods prevents further cell death, Nanotechnology, 17, 4431-4435 (2006)
  3. Syuhei Shigaki, Tatsuhiko Sonoda, Takeyuki Nagashima, Osamu Okitsu, Yasuhiro Kita, Takuro Niidome, Yoshiki Katayama, A new method for evaluation of intracellular protein kinase signals using mass spectrometry, Science and Technology of Advanced Materials 7, 699－704 (2006)
  4. Kenji Kawamura, Jun Oishi, Shigeki Sakakihara, Takuto Niidome, Yoshiki Katayama, Intracellular signal-responsive artificial gene regulation. J. Drug Target., 14, 456-464 (2006)
  5. Jun Oishi, Moeko Ijuin, Tatsuhiko Sonoda, Jeong-Hun Kang, Kenji Kawamura, Takeshi Mori, Takuro Niidome, Yoshiki Katayama, A protein kinase signal-responsive gene carrier modified RGD peptide, Bioorg. Med. Chem. Lett. 16, 5740-5743 (2006)
  6. Takuro Niidome, Masato Yamagata, Yuri Okamoto, Yasuyuki Akiyama, Hironobu Takahashi, Takahito Kawano, Yoshiki Katayama, Yasuro Niidome, PEG-modified gold nanorods with a stealth character for in vivo applications, J. Controlled Release, 114, 343-347 (2006)
  7. Tatsuya Okuda, Shigeru Kawakami, Tadahiro Maeie, Takuro Niidome, Fumiyoshi Yamashita, Mitsuru Hashida, Biodistribution characteristics of amino acid dendrimers and their PEGylated derivatives after intravenous administration, J. Controlled Release, 114, 69-77 (2006)
  8. Tomoko Ito, Naoko Iida-Tanaka, Takuro Niidome, Takahito Kawano, Koji Kubo, Kenichi Yoshikawa, Toshinori Sato, Zhihong Yang, Yoshiyuki Koyama, Hyaluronic acid and its derivative as a multi-functional gene expression enhancer: Protection from non-specific interactions, adhesion to targeted cells, and transcriptional activation, J. Controlled Release, 112, 382-388 (2006)
  9. Shinichi Kuriyama, Yasushi Taguchi, Kanako Nishimura, Kiyoshi Mizuguchi, Kazutoshi Kobayashi, Yoshiki Katayama, Kazutoshi Yanagibashi and Takuro Niidome, Peptide vector for gene delivery with high affinity for phosphatidylserine, J. Peptide Sci., 12, 626-632 (2006)
  10. Hironobu Takahashi, Takuro Niidome, Ayuko Nariai, Yasuro Niidome, Sunao Yamada, Gold Nanorod-Sensitized Cell Death: Microscopic Observation of Single Living Cells Irradiated by Pulsed Near-Infrared Laser Light in the Presence of Gold Nanorods, Chem. Lett. 35, 500-501 (2006)
  11. Jeong-Hun Kang, Riki Toita, Yuhua Jiang, Takuro Niidome, Yoshiki Katayama, Simultaneous analysis of phosphorylated peptides by MALDI-TOF-MS, Chromatographia, 63, 595-598 (2006)
  12. Yasuro Niidome, Takuro Niidome, Sunao Yamada, Yukichi Horiguchi, Hironobu Takahashi, Kanako Nakashima, Pulsed-laser induced fragmentation and dissociation of DNA immobilized on gold nanoparticles, Mol. Cryst. Liq. Cryst., 445, 201-206 (2006)
  13. Takahito Kawano, Masato Yamagata, Hironobu Takahashi, Yasuro Niidome, Sunao Yamada, Yoshiki Katayama, Takuro Niidome, Stabilizing of plasmid DNA in vivo by PEG-modified cationic gold nanoparticles and the gene expression assisted with electrical pulses, J. Controlled Release111, 382-389 (2006)
  14. Aishan Han, Tatsuhiko Sonoda, Jeong-Hun Kang, Masaharu Murata, Takuro Niidome, Yoshiki Katayama, Development of a fluorescence peptide chip for the detection of caspase activity, Comb. Chem. High T. Scr. 9, 21-25 (2006)
  15. Jun Oishi, Kenji Kawamura, Jeong-Hun Kang, Kota Kodama, Tatsuhiko Sonoda, Masaharu Murata, Takuro Niidome, Yoshiki Katayama, An intracellular kinase signal-responsible gene carrier for disordered cell-specific gene therapy, J. Controlled Release 110, 431-436 (2006)
  16. Hironobu Takahashi, Yasuro Niidome, Takuro Niidome, Kenji Kaneko, Hideya Kawasaki, Sunao Yamada, Modification of gold nanorods using phosphatidylcholine to reduce cytotoxicity, Langmuir, 22, 2-5 (2006)
  17. 紫垣修平、韓暁明、山地貴之、山之内豪、森健、新留琢郎、片山佳樹、ペプチドチップを用いる細胞内リン酸化シグナルの蛍光検出、分析化学、55(12)、969-973 (2006)

2005

  1. Tatsuhiko Sonoda, Takuro Niidome, Yoshiki Katayama, Controlled gene delivery responding to cell signals using peptide-polymer conjugates, Recent. Res. Devl. Bioconjugate Chem. 2, 145-158 (2005)
  2. Tatsuhiko Sonoda, Takashi Nogami, Jun Oishi, Masaharu Murata, Takuro Niidome, Yoshiki Katayama, A Peptide Sequence Controls the Physical Properties of Nanoparticles Formed by Peptide-Polymer Conjugates That Respond to a Protein Kinase A Signal, Bioconjugate Chem. 16, 1542-1546 (2005)
  3. Takahito Kawano, Yukichi Horiguchi, Yasuro Niidome, Takuro Niidome, Sunao Yamada, Preparation of Cationic Gold Nanoparticles in Aqueous Solutions of 2-Aminoethanethiol Hydrochloride, Bunseki Kagaku, 54, 521-526 (2005) [Japanese]
  4. Kenji Kawamura, Jun Oishi, Jeong Hun Kang, Kota Kodama, Tatsuhiko Sonoda, Masaharu Murata, Takuro Niidome, Yoshiki Katayama, Intracellular Signal-Responsive Gene Carrier for Cell-Specific Gene Expression, Biomacromolecules. 6, 908-913 (2005)
  5. Takuro Niidome, Noboru Matsuyama, Makoto Kunihara, Tomomitsu Hatakeyama, Haruhiko Aoyagi, Effect of Chain Length of Cationic Model Peptides on Antibacterial Activity, Bull. Chem. Soc. Jpn., 6, 908-913 (2005)

2004

  1. Takahito Kawano, Tatsuya Okuda, Haruhiko Aoyagi, Takuro Niidome, Long Circulation of Intravenously Administered Plasmid DNA Delivered with Dendritic Poly(L-lysine) in the Blood Flow, J. Controlled Release, 99, 329-337 (2004)
  2. Tatsuya Okuda, Takuro Niidome, Haruhiko Aoyagi, Cytosolic Soluble Proteins Induce DNA Release from DNA-Gene Carrier Complexes, J. Controlled Release, 98, 325-332 (2004)
  3. Takuro Niidome, Kanako Nakashima, Hironobu Takahashi, Yasuro Niidome, Preparation of primary amine-modified gold nanoparticles and their transfection ability into cultivated cells, Chem. Commun., 2004, 1978 - 1979 (2004)
  4. Ken-ichi Ogushi, Akihiro Wada, Takuro Niidome, Tatsuya Okuda, Rafael Llanes, Masaaki Nakayama, Yoshito Nishi, Hisao Kurazono, Kelly D. Smith, Alan Aderem, Joel Moss, Toshiya Hirayama, Gangliosides act as co-receptors for Salmonella enteritidis FliC and promote FliC-induction of human b-defensin-2 expression in Caco-2 cells, J. Biol. Chem., 279, 12213-12219 (2004)
  5. Masaaki Nakayama, Miyuki Kimura, Aakihiro Wada, Kinnosuke Yahiro, Ken-ichi Ogushi, Takuro Niidome, A. Fujikawa, D. Shirasaka, N. Aoyama, Hisao Kurazono, M. Noda, Joel Moss, Toshiya Hirayama, Helicobacter pylori VacA activates the p38/ATF-2-mediated signal pathway in AZ521 cells, J. Biol. Chem. 279, 7024-7028 (2004)
  6. Takuro Niidome, Kazuhisa Kobayashi, Hiromi Arakawa, Tomomitsu Hatakeyama, Haruhiko Aoyagi, Structure-Activity Relationship of an Antibacterial Peptide, Maculatin 1.1, from the Skin Glands of the Tree Frog, Litoria genimaculata, J. Peptide Sci. 10, 414-422 (2004)
  7. Tomomitsu Hatakeyama, Tomoko Suenaga, Sei-ishiro Eto, Takuro Niidome, Haruhiko Aoyagi, Antibacterial Activity of Peptides Derived from the C-Terminal Region of a Hemolytic Lectin, from the Murine Invertebrate Cucumaria echinata, J. Biochem., 135, 65-70 (2004)
  8. Kazuo Maruyama, Fumito Iwasaki, Tomoko Takizawa, Hironobu Yanagie, Takuro Niidome, Etsuko Yamada, Tomoko Ito, Yoshiyuki Koyama, Novel Receptor-Mediated Gene Delivery System Comprising Plasmid / Protamine / Sugar-Containing Polyanion Ternary Complex, Biomaterials, 25, 3267-3273 (2004) [2.489, 2001]
  9. Tatsuya Okuda, Akiko Sugiyama, Takuro Niidome, Haruhiko Aoyagi, Characters of Dendritic Poly(L-lysine) Analogues with the Terminal Lysines Replaced with Arginines and Histidines as Gene Carriers in Vitro, Biomaterials, 25, 537-544 (2004) [2.489, 2001]

2003

  1. Koji Kubo, Masatoshi Ichikawa, Yoshiyuki Koyama, Takuro Niidome, Tetsuji Yamaoka, Nomura M. Shinichiro and Kenich Yoshikawa, "Optically Driven Transport into a Living Cell", Appl. Phys. Lett., 83, 2468-2470 (2003) [4.207]
  2. Yumika Fukuoka, Yuko Matsushita, Sachi Furukawa, Takuro Niidome, Tomomitsu Hatakeyama and Haruhiko Aoyagi, "Structure-Activity Relationship of Model Peptides Based on Pleurocidine, an Antibacterial Peptide", Bull. Chem. Soc. Jpn., 76, 1857-1861 (2003) [1.376]
  3. Tatsuya Okuda, Satoru Kidoaki, Mio Ohsaki, Yoshiyuki Koyama, Kenichi Yoshikawa, Takuro Niidome and Haruhiko Aoyagi, "Time-Dependent Complex Formation of Dendritic Poly(L-lysine) with Plasmid DNA and Correlation with in vitro Transfection Efficiencies", Organic & Biomolecular Chemistry, 1, 1270-1273 (2003) [2.023]
  4. Kinnosuke Yahiriro, Akihiro Wada, Masaaki Nakayama, Takahiro Kimura, Ken-ichi Ogushi, Takuro Niidome, Haruhiko Aoyagi, Ken-ichi Yoshino, Kazuhito Yonenaga, Joel Moss and Toshiya Hirayama, "Protein Tyrosine Phosphatase alpha, RPTPalpha, is a Helicobacter pylori VacA Receptor", J. Biol. Chem., 278, 19183-19189 (2003) [7.258]
  5. Yoshiyuki Koyama, Tomoko Ito, Hidetoshi Matsumoto, Akihiko Tanioka,Tatsuya Okuda, Haruhiko Aoyagi and Takuro Niidome, "Novel Poly(ethylene glycol) Derivatives Having Carboxylic Acid Pendant Groups: Syntheses and Their Enhancing Effect on Non-viral Gene Transfection Systems", J. Biomaterials Science: Polymer Edition, 14, 515-532 (2003). [1.234]
  6. Yasuhiro Aoyama, Takuya Kanamori, Takashi Nakai, Toshinori Sasaki, Shohei Horiuchi, Shinske Sando, Takuro Niidome, "Artificial Viruses and Their Application to Gene Delivery. Size-Controlled Gene Coating with Glycocluster Nanoparticles", J. Am. Chem. Soc., 125, 3455-3457 (2003). [6.079]
  7. Xing Yuan, Zheng Ma, Wen Zhou, Takuro Niidome, Sean Alber, Leaf Huang, Simon Watkins, Song Li, "Lipid-Mediated Delivery of Peptide Nucleic Acids to Pulmonary Endothelium", Biochem. Biophys. Res. Commun., 302, 6-11 (2003). [2.946]

2002

  1. Takuro Niidome and Leaf Huang, "Gene Therapy Progress and Prospects: Non-viral Vectors", Gene Ther., 9, 1647-1652 (2002). [5.893]
  2. Mio Ohsaki, Tatsuya Okuda, Akihiro Wada, Toshiya Hirayama, Takuro Niidome, and Haruhiko Aoyagi, "In Vitro Gene Transfection Using Dendritic Poly(L-Lysine)", Bioconjugate Chem., 13, 510-517 (2002). [3.044]
  3. Yasuhiro Mukai, Yuko Matsushita, Takuro Niidome, Tomomitsu Hatekeyama, and Haruhiko Aoyagi, "Parallel and Antiparallel Dimers of Magainin 2: Their Interaction with Phospholipid Membrane and Antibacterial Activity", J. Peptide Sci., 8, 570-577 (2002). [1.451]
  4. 新留琢郎, "遺伝子キャリヤー" , 化学フロンティア５　生命化学のニューセントラルドグマ （杉本編）, 化学同人, pp. 182-191 (2002).

2001

  1. Ken-ichi Ogushi, Akihiro Wada, Takuro Niidome, Naoki Mori, Kazunori Oishi, Tsuyoshi Nagatake, Akira Takahashi, Hiroshi Asakura, Sou-ichi Makino, Hironobu Hojo, Yoshiaki Nakahara, Mio Ohsaki, Tomomitsu Hatakeyama, Haruhiko Aoyagi, Hisao Kurazono, Joel Moss, and Toshiya Hirayama, "Salmonella enteritidis FliC (flagella filament protein) induces human beta-defensin-2 (hBD-2) mRNA production by Caco-2 cells", J. Biol. Chem. 276 (32), 30521-30526 (2001). [7.258]
  2. Takuro Niidome, Hiroto Murakami, Masahito Kawazoe, Tomomitsu Hatakeyama, Yoshihiro Kobashigawa, Minako Matsushita, Yasuhiro Kumaki, Makoto Demura, Katsutoshi Nitta, and Haruhiko Aoyagi, "Carbohydrate Recognition of Gramicidin S Analogs in Aqueous Medium", Bioorg. Med. Chem. Lett. 11, 1893-1896 (2001). [1.747]
  3. Miyuki Kimura, Shinji Goto, Y. Ihara, Akihiro Wada, Kinnosuke Yahirao, Takuro Niidome, Haruhiko Aoyagi, Toshiya Hirayama, and Takehito Kondo, "Impairment of glutathione metabolism in human gastric epithelial cells treated with vacuolating cytotoxin from Helicobacter pylori", Microb. Pathog. 31, 29-36 (2001). [2.061]
  4. Takuro Niidome and Haruhiko Aoyagi, " Cationic alpha-Helical Peptides for Gene Delivery into Cells", Non-viral gene therapy, a volume of Methods in Molecular Medicine (M. A. Findeis, Ed.), 65, 11-21, Humana Press, Inc., NJ, USA.
  5. Yumiko Hori, Makoto Demura, Mitsuo Iwadate, A.S. Ulrich, Takuro Niidome, Haruhiko Aoyagi, Tetsuo Asakura, "Interaction of Mastoparan with Membranes Studied by 1H-NMR in Detergent Micelles and by Solid State 2H- and 15N-NMR in Oriented Lipid Bilayers", Eur. J. Biochem., 268, 302-309 (2001). [2.849]
  6. Yoko Tokunaga, Takuro Niidome, Tomomitsu Hatakeyama, Haruhiko Aoyagi, "Antibacterial Activity of Bactenecin 5 Fragments and their Interaction with Phospholipid Membranes", J. Peptide Sci., 7, 297-304 (2001). [1.451]
  7. Kazutoshi Yoshida, Yasuhiro Mukai, Takuro Niidome, Chinami Takashi, Yoko Tokunaga, Tomomitsu Hatakeyama, Haruhiko Aoyagi, "Interaction of Pleurocidin and its Analogs with Phospholipid Membrane and their Antibacterial Activity", J. Peptide Res., 57, 119-126 (2001). [1.552]

2000

  1. Takuro Niidome, Masashi Tsuiki, Yoko Tokunaga, Tomomitsu Hatakeyama, Haruhiko Aoyagi, "Antibacterial Activity of Arg/Pro-rich Bactenecin 5 Model Peptides and Their Interaction with Phospholipid Membranes", Bull. Chem. Soc. Jpn., 73, 1397-1402 (2000) [1.376]
  2. Takuro Niidome, Mamiko Urakawa, Haruya Sato, Yoshiyuki Takahara, Toyoaki Anai, Tomomitsu Hatakayama, Akihiro Wada, Toshiya Hirayama, Haruhiko Aoyagi, "Gene Transfer into Hepatoma Cells Mediated by Galactose-Modified alpha-Helical Peptides", Biomaterials, 21, 1811-1819 (2000) [2.489]
  3. Philip Ian Padilla, Akihiko Wada, Kinnosuke Yahiro, Miyuki Kimura, Takuro Niidome, Haruhiko Aoyagi, Atsushi Kumatori, Masanobu Anami, Tomoyoshi Hayashi, Jun-ichi Fujisawa, Haruo Saito, Joel Moss and Toshiya Hirayama, "Morphorgic Differentiation of HL-60 Cells is Associated with Appearance of RPTPbeta and Induction of Helicobacter pylori VacA Sensitivity", J. Biol. Chem., 275, 15200-15206 (2000) [7.258]
  4. Takuro Niidome, Masato Wakamatsu, Akihiro Wada, Toshiya Hirayama, Haruhiko Aoyagi, "Required Structure of Cationic Peptide for Oligonucleotide-Binding and -Delivering into Cells", J. Peptide Sci., 6, 271-279 (2000) [1.451]
  5. 新留琢郎、合成ペプチドを使った培養細胞へのトランスフェクション法、和光純薬時報, vol.68, No. 3 (2000).

1999

  1. Takuro Niidome and Haruhiko Aoyagi, "Membrane-Perturbing and -Fusogenic Activities of Amphiphilic Halical Peptides and their Usage in Gene Delivery Systems into Cells", Current Topics in Peptide & Protein Research, 9, 79-89 (1999)
  2. Kinnosuke Yahiro, Takuro Niidome, Miyuki Kimura, Tomomitsu Hatakeyama, Haruhiko Aoyagi, Hisao Kurazono, Ken-ichi Imagawa, Akihiro Wada, Joel Moss and Toshiya Hirayama, "Activation of Helicobacter pylori Vac A Toxin by Alkaline or Acid Conditions Increases its Binding to a 250-kDa Receptor Protein, Tyrosine Phosphatase (RPTP) beta", J. Biol. Chem., 274, 36693-36699 (1999) [7.258]
  3. Takuro Niidome, Mamiko Urakawa, Keiko Takaji, Yukari Matsuo, Naoya Ohmori, Akihiro Wada, Toshiya Hirayama and Haruhiko Aoyagi, "Influence of Lipophilic Groups in Cationic alpha-Helical Peptides on Their Abilities to Bind with DNA and Deliver Gene into Cells", J. Peptide Res., 54, 361-367 (1999) [1.552]
  4. Takuro Niidome, Keiko Takaji, Mamiko Urakawa, Naoya Ohmori, Akihiro Wada, Toshiya Hirayama and Haruhiko Aoyagi, "Chain Length of Cationic alpha-Helical Peptide Sufficient for Gene Delivery into Cells", Bioconjugate Chem., 10, 773-780 (1999) [3.044]
  5. Kazutoshi Yoshida, Naoya Ohmori, Yasuhiro Mukai, Takuro Niidome, Tomomitsu Hatakeyama and Haruhiko Aoyagi, "Interaction of Bundled Ser-Rich Amphiphilic Peptides with Phospholipid Membranes", J. Peptide Sci., 5, 360-367 (1999) [1.451]
  6. Akihiro Wada, Naoki Mori, Kazunori Oishi, Hironobu Hojo, Yoshiaki Nakahara, Yoichi Hamanaka, Masahiro Nagashima, Ichiro Sekine, Ken-ichi Ogushi, Takuro Niidome, Tsuyoshi Nagatake, Joel Moss and Toshiya Hirayama, "Induction of Human beta-Defensine-2 mRNA Expression by Helicobacter pylori in Human Gastric Cell Line MKN45 Cells on cag Pathogenecity Island", Biochem. Biophys. Res. Commun., 263, 770-774 [2.946]
  7. Takuro Niidome, Shingo Anzai, Junko Sonoda, Yoko Tokunaga, Masaaki Nakahara, Tomomitsu Hatakeyama, and Haruhiko Aoyagi, "Effect of Amino Acid Substitution in Amphiphilic alpha-Helical Peptides on Peptide-Phospholipid Membrane Interaction", J. Peptide Sci., 5, 298-305 (1999) [1.451]
  8. Tomomitsu Hatakeyama, Tetsuji Kamine, Yuko Konishi, Hiromiki Kuwahara, Takuro Niidome, and Haruhiko Aoyagi, "Carbohydrate-Dependent Hemolytic Activity of the Conjugate Composed of a C-Type Lectin, CEL-I, and an Amphiphilic alpha-Helical Peptide, 43-betaAla2", Biosci. Biotechnol. Biochem., 63, 1312-1314 (1999) [0.868]
  9. Yumiko Hori, Makoto Demura, Takuro Niidome, Haruhiko Aoyagi and Tetsuo Asakura, "Orientational Behavior of Phospholipid Membranes with Mastoparan Studied by 31P Solid State NMR", FEBS Lett., 455, 228-232 (1999) [3.644]
  10. Tomomitsu Hatakeyama, Taiji Sato, Etsuyo Taira, Hiromiki Kuwahara, Takuro Niidome, and Haruhiko Aoyagi, "Characterization of the Interaction of Hemolytic Lectin CEL-III from the Marine Invertebrate, Cucumaria echinata, with Artificial Lipid Membranes: Involvement of Neutral Sphingoglycolipids in the Pore-Forming Process ", J. Biochem., 125, 277-284 (1999) [1.990]
  11. Miyuki Kimura, Shinji Goto, Akihiro Wada, Kinnosuke Yahiro, Takuro Niidome, Tomomitsu Hatakeyama, Haruhiko Aoyagi, Toshiya Hirayama, and Takehito Kondo, "Vacuolating Cytotoxin Purified from Helicobacter pylori Causes Mitochondrial Damage in Human Gastric Cells", Microb. Pathog., 26, 45-52 (1999) [2.061]

1998

  1. Naoya Ohmori, Takuro Niidome, Taira Kiyota,  Sannamu Lee,  Gohsuke Sugihara,  Akihiro Wada, Toshiya Hirayama, and Haruhiko Aoyagi, "Importance of Hydrophobic Region in Amphiphilic Structures of alpha-Helical Peptides for Their Gene Transfer-Ability into Cells", Biochem. Biophys. Res. Commun., 245, 259-265 (1998)
  2. Takuro Niidome, Hisakazu Mihara, Masahito Oka, Toshio Hayashi, Tetsunobu Saiki, Kazutoshi Yoshida, and Haruhiko Aoyagi, "Structure and Property of Model Peptides of Proline / Arginine-rich Region in Bactenecin 5", J. Peptide Res., 51, 337-345 (1998)
  3. Naoya Ohmori, Takuro Niidome, Tomomitsu Hatakeyama, Hisakazu Mihara, and Haruhiko Aoyagi, "Interaction of alpha-Helical Peptides with Phospholipid Membrane: Effects of Chain Length and Hydrophobicity of Peptides", J. Peptide Res., 51, 103-109 (1998)

1997

  1. Kinnosuke Yahiro, Takuro Niidome, Tomomitsu Hatakeyama, Haruhiko Aoyagi, Hisao Kurazono, Philip Ian Padilla, Akihiro Wada, and Toshiya Hirayama, "Helicobacter pylori Vacuolating Cytotoxin (Vac A) Binds to the 140kDa Protein in Human Gastric Cancer Cell Lines, AZ-521 and AGS", Biochem. Biophys. Res. Commun., 238, 629-632 (1997)
  2. Takuro Niidome, Rie Kawakami, Kinya Okamoto, Naoya Ohmori, Hisakazu Mihara, and Haruhiko Aoyagi, "Interaction of Lipophilic Peptides Derived from Mastoparan with Phospholipid Vesicles", J. Peptide Res., 50, 458-464 (1997)
  3. Tetsuro Fujisawa, Hiromiki Kuwahara, Yasuaki Hiromasa, Takuro Niidome, Haruhiko Aoyagi, and Tomomitsu Hatakeyama, "Small-Angle X-Ray Scattaring study on CEL-III, a Hemolytic Lectin from Holothuroidea Cucumaria echinata, and its Oligomer Induced by the Binding of Specific Carbohydrate", FEBS Lett., 414, 79-83 (1997)
  4. Takuro Niidome, Miyuki Kimura, Tomomi Chiba, Naoya Ohmori, Hisakazu Mihara, and Haruhiko Aoyagi, "Membrane interaction of synthetic peptides related to the putative fusogenic region of PH-30alpha, a protein in sperm-egg fusion", J. Peptide Res., 49, 563-569 (1997)
  5. Naoya Ohmori, Takuro Niidome, Akihiro Wada, Toshiya Hirayama, Tomomitsu Hatakeyama, Haruhiko Aoyagi, "The Enhance Effect of Anionic alpha-Helical Peptide on Cationic Peptide-Mediating Transfection Systems", Biochem. Biophys. Res. Commun., 235, 726-729 (1997)
  6. Takuro Niidome, Naoya Ohmori, Akitoyo Ichinose, Akihiro Wada, Hisakazu Mihara, Toshiya Hirayama, and Haruhiko Aoyagi, "Binding of Cationic alpha-Helical Peptides to Plasmid DNA and Their Gene Transfer Abilities into Cells", J. Biol. Chem., 272,15307-15312 (1997)
  7. Tatsuya Oda, Misao Tsuru, Tomomitsu Hatakeyama, Haruna Nagatomo, Tsuyoshi Muramatsu, and Nobuyuki Yamasaki, "Temperature- and pH-dependent cytotoxic effect of the hemolytic lectin CEL-III from the marine invertebrate Cucumaria echinata on various cell lines", J. Biochem., 121, 560-567 (1997)
  8. Tomomitsu Hatakeyama, Yoko Miyamoto, Haruna Nagatomo, Imure Sallay, and Nobuyuki Yamasaki, "Carbohydrate-binding properties of the hemolytic lectin CEL-III from the Holothuroidea Cucumaria echinata as analyzed using the carbohydrate-coated microplate", J. Biochem., 121, 63-67 (1997)

1996

  1. A. Wada, M. Hasegawa, K. Matsumoto, T. Niidome, Y. Kawano, Y. Hidaka, P. I. Padilla, H. Kurazono, Y. Shimonishi, T. Hirayama, "The Significance of Ser1029 of the Heat-Stable Enterotoxin Receptor (STaR): Relation of STa-Mediated Guanylyl Cyclase Activation and Signaling by Phorbol Myristate Acetate", FEBS Lett., 384(1), pp.75-77 (1996)

1995

  1. H. Mihara, S. Maeda, R. Kurosaki, S. Ueno, S. Sakamoto, T. Niidome, H. Hojo, S. Aimoto, H. Aoyagi, "Peptide Synthesis Mediated by Thiolsubtilisin using Peptide Thioester as Building Block", Chem. Lett., (5), pp.397-398 (1995)
  2. H. Mihara, H. Kuwahara, T. Niidome, H. Kanegae, H. Aoyagi, "Synthesis of Protected Peptides Containing Phosphoserine with Oxime Resin", Chem. Lett., (5), pp.399-400 (1995)
  3. S. Kitada, K. Shimokata, T. Niidome, T. Ogishima, A. Ito,"A Putative Metal-Binding Site in the b Subunit of Rat Mitochondrial Processing Peptidase Is Essential for Its Catalytic Activity", J. Biochem., 117(6), 1148-1150 (1995)
  4. T. Ogishima, T. Niidome, K. Shimokata, S. Kitada, A. Ito, "Analysis of Elements in the Substrate Required for Processing by Mitochondorial Processing Peptidase"，J. Biol. Chem., 270(51), pp.30322-30326 (1995)
  5. H. Mihara, S. Yamabe, T. Niidome, H. Aoyagi, "Efficient Preparation of Cyclic Peptide Mixtures by Solid Phase Synthesis and Cyclization Cleavage with Oxime Resin", Tetrahedron Lett., 36, pp.4837-4840 (1995)
  6. S. Sakamoto, H. Mihara, E. Matsuo, T. Niidome, K. Anzai, Y. Kirino, H. Aoyagi, "Enhanced Membrane Perturbing Activities of Bundled Amphiphilic a-Helix Polypeptides on Interaction with Phospholipid Bilayer", Bull. Chem. Soc. Jpn., 68(10), pp.2931-2939 (1995)

1994

  1. W. Ou, T. Kumamoto, K. Mihara, S. Kitada, T. Niidome, A. Ito, T. Omura, "Structural Requirement for Recognition of the Precursor Proteins by the Mitochondrial Processing Peptidase", J. Biol. Chem., 269, pp.24673-24678 (1994)
  2. T. Niidome, S. Kitada, K. Shimokata, T. Ogishima, A. Ito, "Arginine Residues in the Extension Peptide are Required for Cleavage of a Precursor by Mitochondrial Processing Peptidase. Demonstration Using Synthetic Peptide as a Substrate", J. Biol. Chem., 269, pp.24719-24722 (1994)

1993

  1. T. Uchikoba, T. Niidome, I. Sata and M. Kaneda, Protease D from the Sarcocarp of Honeydew Melon Fruit, Phytochemistry, 33, 1005-1008 (1993)
  2. K. Sakae, T. Niidome, T. Nagano, T. Ogishima and A. Ito, Molecutar Cloning of the Smaller Subunit(P52) of Rat Liver Mitochondrial Processing Protease, Biochem. Biophys. Res. Commun., 190, 289-293 (1993)

1990

  1. T. Niidome, N. Yoshida, F. Ogata, A. Ito and K. Noda, Purification and Characterization of an Acidic Amino Acid-Specific Endopeptidase of Bacillus subtilis. Obtained from a Commercial Preparation (Protease Type XVI, Sigma), J. Biochem., 108, 965-970 (1990)

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  10. 科学研究費補助金（基盤研究C）（研究分担者）2003年４月～2006年３月、「臨床応用を目的とした局所用遺伝子製剤の理論的開発」
  11. 科学研究費補助金（基盤研究C）（研究分担者）2002年４月～2004年３月、「ペプチド-DNA複合体を用いる簡便かつ高効率なトランスフェクション試薬の開発」
  12. 科学研究費補助金（若手研究A）（研究代表者）2002年４月～2004年３月、「遺伝子・遺伝子キャリアー複合体の細胞内でのトラフィックコントロール」
  13. 科学研究費補助金（特定領域研究C-2（がん研究））（研究代表者）2000年４月～2001年３月、「遺伝子治療用核酸キャリアー分子開発に関する基礎研究」
  14. 科学研究費補助金（奨励研究A）（研究代表者）、1999年４月～2001年３月、「肝細胞選択的な遺伝子導入を可能にする新規ペプチド性核酸キャリアーの構築」
  15. 科学研究費補助金（奨励研究A）（研究代表者）、1997年４月～1999年３月、「細胞選択的遺伝子導入を可能にするペプチド性核酸キャリアーの構築」

新聞、雑誌

  1. がん細胞へ導入効率アップ、新人工ベクターを開発、日刊工業新聞、2003年１２月１９日、27面
  2. Cell mail delivery by light, Nature, vol. 25, p364 (2003)
  3. 細胞内への遺伝子導入、光ピンセットで非接触、日刊工業新聞、2003年3月20日、４面
  4. ペプチド、ミトコンドリアに導入、長崎大、遺伝子治療に応用、日経産業新聞、2003年2月25日、12面
  5. 細胞内にDNA搬入、京大など遺伝子治療に応用、日経産業新聞、2003年2月14日、11面
  6. ハイテクうらばなし、テーラーメードバイオ、遺伝子デリバリー、日刊工業新聞、2002年10月８日、５面
  7. 導入効率３倍の高分子ベクター、日経産業新聞、2001年8月29日、12面
  8. 遺伝子治療向けに新材料、DNAの分解を防ぐ、日経産業新聞、1998年１２月１日、５面
  9. 膜透過ペプチドでアンチセンス取り込み成功、日経バイオテク、1997年１２月１日、p. 10